The Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study has recently .. (Estudio SECCAID: Spain estimated cost Ciberdem-Cabimer in Diabetes). Background Obesity and gestational diabetes mellitus (GDM) increase the Recently the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study7,8 .. grant from the IdISSC and the Fundación para Estudios Endocrinometabólicos. [New diagnostic criteria for gestational diabetes mellitus after the HAPO study. . de los estudios desarrollados por el Grupo Español de Diabetes y Embarazo.

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Study methods have been published previously 129. For both measures of neonatal adiposity, there was a strong graded association across increasing levels of maternal glycemia.

Received Aug 14; Accepted Nov Management diaebtes obesity in pregnancy. Personnel were trained during regional training sessions run by Clinical and Data Coordinating Center staff.

Anthropometric estimation of neonatal body composition. In model I, the OR was 6. For these analyses, the average of the two measurements was used, unless a third measurement was taken.

The Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study.

Secondhand exposure to aerosol from electronic cigarettes: Subcutaneous fat in newborn infants of diabetic mothers: A brief overview is presented here. Open in a separate window. A training videotape providing instruction in anthropometric measurements was viewed.


All pregnant women at each field center were eligible to participate unless they had one or more exclusion criteria 2: Si continua navegando, consideramos que acepta su uso.

With higher levels of cord C-peptide, frequency of each measure of size and adiposity rose.

Effects of hyperinsulinemia on the primate fetus. Neonatal anthropometrics and cord serum C-peptide were measured. These limitations preclude our ability to evaluate the differential effects of pre-existing obesity and maternal weight gain in contributing to the outcomes measured. Haemolysis affects insulin but not C-peptide immunoassay. Correlations among the glucose measures were modest 2and an index of their integrated associations with these anthropometric outcomes is not available.

Thus, it is not surprising diqbetes associations of each glucose measure with anthropometric outcomes were significantly reduced but not eliminated when adjusted for cord C-peptide. Factors affecting fetal growth and body composition. Hyperglycemia and adverse pregnancy outcomes. In model I, ORs for the three measures ranged from 5.

The Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study.

An external data monitoring committee provided oversight. For measures of neonatal adiposity, there were strong statistically significant gradients across increasing levels of maternal glucose and cord serum C-peptide, which persisted after adjustment for potential confounders. All participants gave written informed consent. Strongest associations were with subscapular skin fold where ORs for each glucose measure higher by 1 SD ranged from 1.


Rosa Corcoy ab ,?? Show all Show less. Prepregnancy body weight was self-reported and incomplete, and weight was not measured at delivery, making maternal weight gain unavailable in a large number of cases. Results for both model I and model II show that subscapular skin fold has the strongest and flank skin fold the weakest association with cord C-peptide level, with ORs for the highest versus lowest category of 6.

Of pregnancy and progeny.


The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two receding years. There estudjo, however, a significant interaction of 1-h plasma glucose with age in the model II analysis for triceps skin fold, which suggested a stronger association of 1-h plasma glucose dlabetes triceps skin fold with increasing maternal age. For glucose as a continuous variable, odds ratios ORs were calculated for each measure fasting, 1- and 2-h plasma glucose higher by 1 SD.